CD38 as a molecular marker on macrophages for COPD, and as a target molecule for treatment of COPD

摘要

The present invention relates to use of CD38 as a biomarker for COPD. The invention also relates to methods of using compounds acting as CD38 modulators in the prevention and treatment of COPD. In addition, the invention provides methods and kits of diagnosis, prognosis, monitoring and assessment of the efficacy of a treatment for COPD using quantification of CD38 expression and/or activity levels.