| 发明名称 |
1,5-DISUBSTITUTED PYRROLID-2-ONE DERIVATIVES FOR USE AS EP4 RECEPTOR AGONISTS IN THE TREATMENT OF EYE DISEASES SUCH AS GLAUCOMA |
| 摘要 |
This invention relates to potent selective agonists of the EP4 subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions which are related to elevated intraocular pressure in the eye of a patient. |
| 申请公布号 |
EP1513589(A1) |
申请公布日期 |
2005.03.16 |
| 申请号 |
EP20030727099 |
申请日期 |
2003.06.02 |
| 申请人 |
MERCK FROSST CANADA INC. |
发明人 |
BILLOT, XAVIER;YOUNG, ROBERT, N.;HAN, YONGXIN |
| 分类号 |
C07D403/06;A61K31/13;A61K31/137;A61K31/138;A61K31/382;A61K31/4015;A61K31/41;A61K31/416;A61K31/4164;A61K31/4168;A61K31/4178;A61K31/433;A61K31/4412;A61K31/498;A61K31/5377;A61K31/5575;A61K31/559;A61K45/00;A61K45/06;A61P3/14;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P25/02;A61P27/02;A61P27/06;A61P29/00;A61P35/00;A61P43/00;C07D207/26;C07D403/12;(IPC1-7):A61P27/06;A61K31/401 |
主分类号 |
C07D403/06 |
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