发明名称 (2S)-2-(adamantan-1-ylmethoxycarbonylamino)-3-(4-(2-(1,4,5,6-tetrhydropyrimidin-2-ylcarbamoyl)ethyl)benzoylamino)propionic acid isopropyl ester, its preparation and its use
摘要 (2S)-2-(Adamantan-1-ylmethoxycarbonylamino)-3-(4-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)ethyl)benzoylamino)propionic acid isopropyl ester, its preparation and its useThe present invention relates to (2S)-2-(adamantan-1-ylmethoxycarbonylamino)-3-(4-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)ethyl)benzoylamino)propionic acid isopropyl ester of the formula Iand its physiologically tolerable salts, their preparation, their use as pharmaceuticals and to pharmaceutical compositions comprising them. The compound of the formula I and its physiologically tolerable salts are valuable pharmacologically active compounds which can be used, for example, in the treatment or prophylaxis of diseases which can be influenced by inhibiting the vitronectin receptor, for example of bone diseases such as osteoporosis.
申请公布号 US6867213(B2) 申请公布日期 2005.03.15
申请号 US20030398821 申请日期 2003.07.30
申请人 AVENTIS PHARMA DEUTSCHLAND GMBH;GENENTECH INC. 发明人 PEYMAN ANUSCHIRWAN;WOLLMANN THEODOR;BREJPOHL GERHARD;GOURVEST JEAN-FRANCOIS;RUXER JEAN-MARIE;GADEK THOMAS;MCDOWELL ROBERT
分类号 A61K31/505;A61P9/00;A61P9/10;A61P13/02;A61P19/10;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D239/16;(IPC1-7):A61K31/505;C07D239/02 主分类号 A61K31/505
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