| 发明名称 |
PRODRUGS OF BENZOFURANYLMETHYL CARBAMATE NK, ANTAGONISTS |
| 摘要 |
The instant invention provides aqueous soluble prodrugs of formula (I) or a pharmaceutically acceptable salt thereof wherein R is -CH2OZ, -C(-O)OCH2OZ or Z, wherein Z is formula (a), P(-O)(OH)2 or -C(-O)Q: n is an integer of from 0 to 3; m is an integer of from 0 to 1, of certain tachykinin antagonists (NK1 antagonists) useful in t he treatment of emesis.
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| 申请公布号 |
CA2323047(C) |
申请公布日期 |
2005.03.15 |
| 申请号 |
CA19992323047 |
申请日期 |
1999.03.19 |
| 申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
ZHU, ZHIJIAN;CHAN, OILUN HELEN;CHEN, MICHAEL HUAI GU;HERSHENSON, FRED M.;GOEL, OM PRAKASH |
| 分类号 |
A61K31/405;A61K31/5377;A61K31/675;A61P1/00;A61P1/08;A61P9/10;A61P11/00;A61P11/06;A61P19/02;A61P25/04;A61P25/06;A61P27/02;A61P29/00;A61P37/08;A61P43/00;C07D405/12;C07F9/141;C07F9/145;C07F9/22;C07F9/572;C07F9/6558;(IPC1-7):C07D405/12;A61K31/34 |
主分类号 |
A61K31/405 |
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