发明名称 |
METHOD AND APPARATUS FOR ASSAY OF ELECTROCHEMICAL PROPERTIES |
摘要 |
The presence of a select analyte in the sample is evaluated in an an electrochemical system using a conduction cell-type apparatus. A potential or current is generated between the two electrodes of the cell sufficient to bring about oxidation or reduction of the analyte or of a mediator in an analyte-detection redox system, thereby forming a chemical potential gradient of the analyte or mediator between the two electrodes After the gradient is established, the applied potential or current is discontinued and an analyte-independent signal is obtained from the relaxation of the chemical potential gradient. The analyte-independent signal is used to correct the analyte-dependent signal obtained during application of the potential or current. This correction allows an improved measurement of analyte concentration because it corrects for device-specific and test specific factors such as transport (mobility) of analyte and/or mediator, effective electrode area, and electrode spacing (and as a result, sample volume), without need for separate calibration values. The analysis can be performed using disposable test strips in a hand held meter, for example for glucose testing. |
申请公布号 |
WO2005022143(A2) |
申请公布日期 |
2005.03.10 |
申请号 |
WO2004US27441 |
申请日期 |
2004.08.23 |
申请人 |
AGAMATRIX INC.;IYENGAR, SRIDHAR G;HARDING, IAN |
发明人 |
IYENGAR, SRIDHAR G;HARDING, IAN |
分类号 |
A61B5/00;C12Q1/00;G01N27/416;G01N33/487 |
主分类号 |
A61B5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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