HYDROGELS FOR MODULATING CELL MIGRATION AND MATRIX DEPOSITION
摘要
A biodegradable matrix for inducing cell migration therein, wherein two peptides are covalently linked to the matrix, a first peptide being cleavable by natural proteases and the other comprising a cell-attracting peptide. The first peptide is cleavable by tissue metalloproteinases. The second peptide contains the cell-attracting peptide RGD. Also disclosed is an implant containing the biodegradable matrix.
申请公布号
WO2005021580(A2)
申请公布日期
2005.03.10
申请号
WO2004US28000
申请日期
2004.08.27
申请人
ARIZONA BOARD OF REGENTS;KENNEDY, CHAD;EHTESHAMI, GHOLAM, REZA;HOM, DORIS;MASSIA, STEPHEN
发明人
KENNEDY, CHAD;EHTESHAMI, GHOLAM, REZA;HOM, DORIS;MASSIA, STEPHEN