摘要 |
A compound represented by the following general formula (I): (wherein R<1 >represents phenyl, etc. which can have substituents selected from the group consisting of C1-8 alkyl, C1-8 alkyl having halogen, halogen, hydroxyl, etc.; R<2 >represents C1-8 alkyl, etc.; A represents oxygen, sulfur, etc.; X represents C1-8 alkylene chain, etc.; Y represents C(=O), CH=CH, etc.; R<3>, R<4>, and R<5 >each represents hydrogen, C1-8 alkyl, etc.; B represents CH or nitrogen; Z represents oxygen or sulfur; R<6 >and R<7 >each represents hydrogen, C1-8 alkyl, etc.; and R<8 >represents hydrogen or C1-8 alkyl; provided that at least one of R<3>, R<4>, and R<5 >is not hydrogen) or a salt of the compound; and a PPAR-delta activator which contains the compound or salt as the active ingredient. |