INDIRECT DELIVERY OF GROWTH FACTORS INTO THE CENTRAL NERVOUS SYSTEM

摘要

The present invention provides a method of delivering a treatment to the central nervous system, including the steps of administering a therapeutic intramuscularly into muscles innervated by nerves chosen from the group consisting of cranial nerves and spinal nerves, and transporting the therapeutic peripherally through nerves into the CNS and to the site of treatment. The present invention provides a method of treating a neural disorder or a part of the body by administering an effective amount of a compound affecting neural cells into muscles innervated by cranial and/or spinal nerves, and affecting neural cells. The present invention also provides a method of treating a spinal cord injury by administering an effective amount of a compound affecting neural cells into musculature directly innervated by the spinal cord, and affecting neural cells. The present invention further provides a method of treating Parkinson's disease by administering an effective amount of a compound affecting neural cells into musculature innervated by the motor trigeminal nerve, and affecting neural cells involved in Parkinson's disease. Finally, the present invention also provides a method of treating amyotrophic lateral sclerosis by administering an effective amount of a compound affecting neural cells into musculature innervated by cranial and/or spinal nerves, and affecting neural cells involved in amyotrophic lateral sclerosis.