发明名称 АЗОЛЫ В КАЧЕСТВЕ ИНГИБИТОРОВ МАЛОНИЛ-СОА-ДЕКАРБОКСИЛАЗЫ, ПОЛЕЗНЫЕ В КАЧЕСТВЕ МОДУЛЯТОРОВ МЕТАБОЛИЗА
摘要 The present invention relates to methods of treatment of certain metabolic diseases, and to the use of compounds and their prodrugs, and/or pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds useful in treating such diseases. In particular, the invention relates to the use of compounds and compositions for treatment of cardiovascular diseases, diabetes, cancers, acidosis, and obesity through the inhibition of malonyl-CoA decarboxylase (MCD). These compounds have the following formulae: (I) and (II) Wherein Y, C, R1, R2, R6, and R7 are defined herein.
申请公布号 RU2003128307(A) 申请公布日期 2005.03.10
申请号 RU20030128307 申请日期 2002.02.19
申请人 ЧУГАИ СЕЙЯКУ КАБУСИКИ КАЙСЯ (JP) 发明人 АРРХЕНИУС Томас (US);ЧЭН Цзе Фэй (US);УИЛСОН Марк (US);СЕРАФИМОВ Росси (US)
分类号 C07D277/72;A61K31/423;A61K31/425;A61K31/426;A61K31/427;A61K31/428;A61K31/4353;A61K31/4439;A61K31/454;A61K31/496;A61K31/519;A61K31/5377;A61K31/541;A61P3/00;A61P3/04;A61P3/06;A61P3/08;A61P3/10;A61P7/00;A61P9/00;A61P9/04;A61P9/10;A61P35/00;A61P43/00;C07D277/20;C07D277/36;C07D277/56;C07D277/70;C07D277/82;C07D409/12;C07D417/12;C07D513/04 主分类号 C07D277/72
代理机构 代理人
主权项
地址