COMPOUNDS THAT ACT TO MODULATE INSECT GROWTH AND METHODS AND SYSTEMS FOR IDENTIFYING SUCH COMPOUNDS
摘要
Disclosed are methods and systems for screening for compounds that act to modulate insect growth. Bioassays including cell culture and/or transgenic insects engineered with various components of the ecdysoid receptor (EcR) and/or the farsenoid-X receptor (RXR) systems to identify compounds that act as insecticides and/or hormone receptor activators are described. Also described are compounds, and compositions, identified as being putative insecticides based upon their ability to activate EcR and/or FXR mediated transcription.
申请公布号
WO2005022167(A2)
申请公布日期
2005.03.10
申请号
WO2004US28113
申请日期
2004.08.27
申请人
THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO;HENRICH, VINCENT, C.;WEINBERGER, CARY, ALAN