发明名称 Lipid-peptide-polymer conjugates for long blood circulation and tumor specific drug delivery systems
摘要 The present invention relates to conjugates of a lipid, substrate peptide of an enzyme secreted from the cells of mammals, including humans, and a water-soluble polymer that can be used as colloidal carriers and the like of tissue-specific drug delivery systems, methods of producing these conjugates, peptide-water-soluble polymer conjugates optionally having protective groups that are useful as the intermediates of these conjugates, colloidal carriers made from these conjugates, and tissue-specific drug delivery systems that use these colloidal carriers.
申请公布号 US2005054026(A1) 申请公布日期 2005.03.10
申请号 US20040754341 申请日期 2004.01.09
申请人 YAMANOUCHI PHARMACEUTICAL CO., LTD. 发明人 ATSUSHI MAEDA;TAKAGI AKIRA;SAITO KATSUMI;YAMASHITA NOBORU;YOSHIOKA TATSNOBU
分类号 A61K9/127;C07K7/06;(IPC1-7):C12Q1/37;C08G63/48;C08G63/91 主分类号 A61K9/127
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