发明名称 1-(3,4-ДИХЛОРФЕНИЛ)-3-АЗАБИЦИКЛО[3.1.0]ГЕКСАН, ЕГО КОМПОЗИЦИИ И ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРА ОБРАТНОГО ЗАХВАТА ДОПАМИНА
摘要 The present invention relates to (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane and pharmaceutically acceptable salts thereof, compositions comprising (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and methods for treating or preventing a disorder alleviated by inhibiting dopamine reuptake. In one embodiment, the disorder is attention-deficit disorder, depression, obesity, Parkinson's disease, a tic disorder, or an addictive disorder. The (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or pharmaceutically acceptable salt thereof is preferably substantially free of its corresponding (+)-enantiomer.
申请公布号 RU2004108694(A) 申请公布日期 2005.03.10
申请号 RU20040108694 申请日期 2002.08.14
申请人 ДОВ ФАРМАСЬЮТИКАЛ, ИНК. (US) 发明人 ЛИППА Арнольд Стэн (US);ЭПСТЭЙН Джозеф Уилль мс (US)
分类号 C07D471/08;A61K9/14;A61K31/439;A61K45/00;A61P3/04;A61P25/00;A61P25/16;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P25/34;A61P25/36;A61P43/00;C07D209/52 主分类号 C07D471/08
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