| 发明名称 |
ENHANCING THE CIRCULATING HALF-LIFE OF INTERLEUKIN-2 PROTEINS |
| 摘要 |
The present invention relates generally to novel interleukin-2 proteins, including fusion proteins, based on two or more amino acids alterations in the N-terminal region of the IL-2 protein, and, more specifically, to methods of enhancing the circulating half-life by means of these interleukin-2 proteins. |
| 申请公布号 |
WO2005021592(A2) |
申请公布日期 |
2005.03.10 |
| 申请号 |
WO2004EP09642 |
申请日期 |
2004.08.30 |
| 申请人 |
MERCK PATENT GMBH;GILLIES, STEPHEN;LAUDER, SCOTT;WAY, JEFFREY |
发明人 |
GILLIES, STEPHEN;LAUDER, SCOTT;WAY, JEFFREY |
| 分类号 |
A61K38/20;A61K39/00;C07H21/04;C07K14/54;C07K14/55;C12P21/04 |
主分类号 |
A61K38/20 |
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