Method for determining the impact of a multicomponent mixture on the biological profile of a disease

摘要

The present invention provides a method for determining the impact of a multicomponent mixture on a biological profile of a disease comprising the steps of: (a) determining a biological profile of the disease by comparing the biological profile of a group with symptoms of the disease with the biological profile of a reference (or healthy) group, using a multivariate analysis; (b) determining the impact of a series of samples of the multicomponent mixture on the biological profile of the disease, in which respective samples the concentrations of various components differ, using a multivariate analysis; (c) determining the composition of the samples of the multicomponent mixture that have shown in step (b) an impact on the biological profile of the disease, using a multivariate analysis; (d) identifying within the compositions as determined in step (c) the effective components and their respective concentrations required for having an impact on the biological profile of the disease, using a multivariate analysis. The invention also provides a method for preparing a medicament for treating a disease, wherein the effective components as identified in step (d) are combined in the respective concentrations required for having an impact on the biological profile of the disease. The invention further provides a method for controlling the composition of a multicomponent mixture, wherein the concentrations of at least two components of the mixture are adjusted to ensure that the at least two components of the mixture have an impact on a biological profile of the disease.