| 发明名称 |
Benzopyranverbindingen toepasbaar voor het behandelen van ontstekingsaandoeningen. |
| 摘要 |
The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, and R<SUP>4 </SUP>are as described in the specification. |
| 申请公布号 |
NL1028308(A1) |
申请公布日期 |
2005.03.09 |
| 申请号 |
NL20051028308 |
申请日期 |
2005.02.16 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
JEFFERY STEVEN CARTER;KARL WILLIAM ASTON;DAVID LOUIS BROWN;ANGELA M. DEPROW;THERESA R. FLETCHER;E. ANN HALLINAN;BRUCE CAMERON HAMPER;RENEE M. HUFF;JAMES RICHARD KIEFER, JR.;FRANCIS KOSZYK;STEVEN W. KRAMER;SUBO LIAO;DAVID CHRISTOPHER LIMBURG;CINDY LUDWIG;JOHN MICHAEL MCCALL;JOHN ROBERT SPRINGER;JOHN T. TALLEY;LIJUAN JANE WANG;LI XING;YI YU |
| 分类号 |
A61K31/352;A61K31/382;A61K31/395;A61K31/47;A61K31/4709;A61P29/00;C07D;C07D215/38;C07D215/54;C07D311/58;C07D311/64;C07D311/92;C07D335/06;C07D401/02;C07D405/02;C07D407/02;C07D409/02;C07D493/04 |
主分类号 |
A61K31/352 |
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