SYSTEM AND METHOD FOR ANALYZING BIO CHIP THROUGH HIERARCHICAL STRUCTURE MODEL OF GO

摘要

PURPOSE: A system and a method for analyzing a bio chip through a hierarchical structure model of the GO(Gene Ontology) are provided to systematically perform biological analysis for a gene expression pattern of a DNA(Deoxyribo Nucleic Acid) chip experiment by modeling a GO hierarchical structure. CONSTITUTION: A GO terminology assigner(202) assigns a related GO terminology to each genes included in each cluster by receiving a statistical clustering result of the bio chip experiment result. A GO code converter(204) converts the assigned GO terminology into a GO code, which is a preset numeric combination. A biological meaning extractor(206) determines the GO terminology optimally matched with the cluster by calculating a pseudo distance between one GO terminology on a GO tree structure included in a preset group and the GO terminologies corresponding to the genes included in the cluster, calculating at least one of an average pseudo distance or a maximum pseudo distance of the calculated pseudo distances, and calculating at least one of the average pseudo distance or the maximum pseudo distance for all terminologies on the GO tree structure included in the preset group.