发明名称 |
A HUMAN CELL ASSAY TO DETERMINE EFFECT OF SAMPLE COMPOUNDS ON COL2 ENHANCER EXPRESSION. |
摘要 |
<p>This invention relates to human chondrocyte activity (growth)/differentiation/production of extracellular matrix) and to the effect of Sox9transcription factor and Colt enhancer as a measure for such activity. It also relates to a chimeric cell and assay utilizing such cell useful in predicting the effect of sample compounds on chondrocyte activity as measured by Sox9 and Colt expression/activity.</p> |
申请公布号 |
MXPA04012042(A) |
申请公布日期 |
2005.03.07 |
申请号 |
MX2004PA12042 |
申请日期 |
2003.05.26 |
申请人 |
PFIZER PRODUCTS INC. |
发明人 |
SCHAEFER, JEAN FRANCES |
分类号 |
C07K14/47;C12Q1/68;(IPC1-7):C12N00/00 |
主分类号 |
C07K14/47 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|