发明名称 |
Optical sampling interface system for in vivo measurement of tissue |
摘要 |
An optical sampling interface system minimizes and compensates error resulting from sampling variations and measurement site state fluctuations. Components include: An optical probe placement guide having an aperture wherein the optical probe is received, facilitates repeatable placement accuracy on surface of a tissue measurement site with minimal, repeatable disturbance to surface tissue. The aperture creates a tissue meniscus that minimizes interference due to surface irregularities and controls variation in tissue volume sampled; an occlusive element placed over the tissue meniscus isolates the meniscus from environmental fluctuations, stabilizing hydration at the site and thus, surface tension; an optical coupling medium eliminates air gaps between skin surface and optical probe; a bias correction element applies a bias correction to spectral measurements, and associated analyte measurements. When the guide is replaced, a new bias correction is determined for measurements done with the new placement. Separate components of system can be individually deployed.
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申请公布号 |
US2005049466(A1) |
申请公布日期 |
2005.03.03 |
申请号 |
US20040917802 |
申请日期 |
2004.08.12 |
申请人 |
BLANK THOMAS B.;ACOSTA GEORGE;MATTU MUTUA;MAKAREWICZ MARCY;MONFRE STEPHEN L.;LORENZ ALEXANDER D.;RUCHTI TIMOTHY L. |
发明人 |
BLANK THOMAS B.;ACOSTA GEORGE;MATTU MUTUA;MAKAREWICZ MARCY;MONFRE STEPHEN L.;LORENZ ALEXANDER D.;RUCHTI TIMOTHY L. |
分类号 |
A61B5/01;A61B;A61B1/00;A61B5/00;A61B5/0205;A61B5/145;A61B5/1455;A61K9/00;G01N21/01;G01N21/35;(IPC1-7):A61B5/00 |
主分类号 |
A61B5/01 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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