IMPROVED ANTIBODIES HAVING ALTERED EFFECTOR FUNCTION AND METHODS FOR MAKING THE SAME
摘要
The invention provides a method of producing aglycosylated Fc-containing polypeptides, such as antibodies, having desired effector function. The invention also provides aglycosylated antibodies produced according to the method as well as methods of using such antibodies as therapeutics.
申请公布号
WO2005018572(A2)
申请公布日期
2005.03.03
申请号
WO2004US27476
申请日期
2004.08.23
申请人
BIOGEN IDEC MA INC.;TAYLOR, FREDERICK, R.;GARBER, ELLEN