发明名称 |
Methods and compositions for modulating NF-AT transcription factor |
摘要 |
This invention provides novel NF-AT-modulatory polypeptides. The invention also provides methods for screening modulators of NF-AT. The methods comprise first screening test agents for modulators of an NF-AT-modulatory polypeptide and then further screening the identified modulating agents for modulators of NF-AT. The invention further provides methods and pharmaceutical compositions for modulating NF-AT bioactivities in a cell and for treating diseases and conditions mediated by abnormal NF-AT activities.
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申请公布号 |
US2005048585(A1) |
申请公布日期 |
2005.03.03 |
申请号 |
US20030732894 |
申请日期 |
2003.12.10 |
申请人 |
IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY |
发明人 |
WHITE SUHAILA;CHANDA SUMIT;CALDWELL JEREMY S. |
分类号 |
A61K;C12Q1/02;C12Q1/68;G01N33/53;G01N33/567;(IPC1-7):G01N33/53 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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