The present invention relates to processes for the preparation of tablets which dissolve rapidly in the mouth and provide an excellent mouthfeel. The tablets of the invention comprise a compound which melts at about 37°C or lower, have a low hardness, high stability and generally comprise few insoluble disintegrants which may cause a gritty or chalky sensation in the mouth. Convenient and economically feasible processes by which the tablets of the invention may be produced are also provided.
申请公布号
WO2005018617(A1)
申请公布日期
2005.03.03
申请号
WO2004US26869
申请日期
2004.08.19
申请人
WYETH;SZAMOSI, JANOS;KINTER, KEVIN, S.;LI, VINCENT, H.