发明名称 |
TREATMENTS FOR LEISHMANIASIS |
摘要 |
A method for the treatment of leishmaniasis, comprising administering a therapeutically effective amount of a compound of Formula I wherein R1, R2, R4 and R5 are H, OH, OR6, or R1 and R2 and/or R4 and R5 together forming a methylenedioxy or other bridging group of the form -O-(CH2)n-O- where n is 1, 2 or 3, where R6 is a carbohydrate residue, phosphate residue, sulfate residue or lower alkyl, and R3 is H or lower alkyl. Lower alkyl may be a linear, branched or cyclic group having less than about 6-10 carbons, optionally including one or more single or double bonds. The method also includes admnistering a pharmaceutically acceptable salt of a compound of Formula I and administration of a pharmaceutical composition containing a compound of Formula I together with one or more pharmaceutically acceptable ingredients. |
申请公布号 |
WO2004084801(A3) |
申请公布日期 |
2005.03.03 |
申请号 |
WO2003US27469 |
申请日期 |
2003.09.04 |
申请人 |
SMITHSONIAN TROPICAL RESEARCH INSTITUTE;RIOS, LUIS, CUBILLA;ROMERO, LUZ, I.;ORTEGA-BARRIA, EDUARDO;CAPSON, TODD |
发明人 |
RIOS, LUIS, CUBILLA;ROMERO, LUZ, I.;ORTEGA-BARRIA, EDUARDO;CAPSON, TODD |
分类号 |
A61K;A61K31/44 |
主分类号 |
A61K |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|