| 摘要 |
<P>PROBLEM TO BE SOLVED: To obtain a prophylactic and therapeutic agent for diabetes mellitus disease and a functional food or food material for prophylaxis/improvement of diabetes mellitus disease, capable of effectively utilizing Alpinia specios K. Schum in which utilization of excellent physiological activity is not sufficiently carried out, being readily available as an ingredient derived from the plant, scarcely having adverse effect on living bodies and having high safety. <P>SOLUTION: This prophylactic and therapeutic agent for the diabetes mellitus disease comprises a fermentation treated substance obtained by fermenting Alpinia specios K. Schum with lactic acid bacterium, lactic acid bacterium and Bacillus subtilis or lactic acid bacterium, yeast and Bacillus subtilis as an active ingredient, and the fermentation treated substance is the substance obtained by carrying out fermentation treatment of its leaf with a mixed bacterium of Lactobacillus plantarum with Streptococcus thermophilus and Bacillus subtilis. The prophylactic and therapeutic agent for diabetes mellitus disease has an action lowering contents of glucose, insulin and total cholesterol and nitrogen monoxide in serum and lowering blood glucose level and lowering renal LPO. <P>COPYRIGHT: (C)2005,JPO&NCIPI |
