发明名称 |
CYCLIC PEPTIDE AND IMAGING COMPOUND COMPOSITIONS AND USES FOR TARGETED IMAGING AND THERAPY |
摘要 |
The present invention relates to novel cyclic peptides that may be conjugated with imaging agents, including novel imaging agents. Specifically, it includes c(KRGDf) NIR imaging compositions and novel cyclic HWGFTL polypeptides which may be used inter alia in NIR, MRI and nuclear imaging as well as therapy. Additionally, the invention includes novel imaging agents, such as TS-ICG derivatives. The invention also relates to methods of making and using such compounds. Such uses include both pre-operative and intraoperative detection of tumor cells and treatment monitoring. |
申请公布号 |
WO2005019247(A2) |
申请公布日期 |
2005.03.03 |
申请号 |
WO2004US26220 |
申请日期 |
2004.08.13 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;LI, CHUN;KE, SHI;WANG, WEI |
发明人 |
LI, CHUN;KE, SHI;WANG, WEI |
分类号 |
A61K49/00;A61K51/08;C07K7/56;C07K14/81 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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