发明名称 |
PGC-1beta, A NOVEL PGC-1 HOMOLOGUE AND USES THEREFOR |
摘要 |
The invention provides isolated nucleic acid molecules, designated PGC-1beta nucleic acid molecules, which encode novel PGC-1 related coactivator molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PGC-1beta nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a PGC-1beta gene has been introduced or disrupted. The invention still further provides isolated PGC-1beta proteins, fusion proteins, antigenic peptides and anti-PGC-1beta antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. |
申请公布号 |
WO03042362(A3) |
申请公布日期 |
2005.03.03 |
申请号 |
WO2002US35869 |
申请日期 |
2002.11.08 |
申请人 |
DANA-FARBER CANCER INSTITUTE, INC.;SPIEGELMAN, BRUCE, M.;LIN, JIANDIE |
发明人 |
SPIEGELMAN, BRUCE, M.;LIN, JIANDIE |
分类号 |
G01N33/50;A61K45/00;A61K48/00;A61P3/10;A61P9/00;A61P25/00;A61P25/16;A61P43/00;C07H21/04;C07K14/47;C07K16/18;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12N9/20;C12N15/09;C12P21/02;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;G01N33/567 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|