发明名称 |
Proteins having serine/threonine kinase domains, corresponding nucleic acid molecules, and their use |
摘要 |
The invention relates to the molecule referred to as ALK-1, and its role as a type I receptor for members of the TGF-beta family. The molecule has a role in the phosphorylation of Smad-5 and Smad1, which also act as activators of certain genes. Aspects of the invention relate to this interaction.
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申请公布号 |
US2005048607(A1) |
申请公布日期 |
2005.03.03 |
申请号 |
US20030739413 |
申请日期 |
2003.12.19 |
申请人 |
MIYAZONO KOHEI;IMAMURA TAKESHE;DIJKE PETER TEN |
发明人 |
MIYAZONO KOHEI;IMAMURA TAKESHE;DIJKE PETER TEN |
分类号 |
A61K38/00;C07K14/71;C07K16/28;(IPC1-7):C07H21/04;C12N9/12;C12N9/16 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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