| 发明名称 |
CRYSTALLIZATION AND PURIFICATION OF MACROLIDES |
| 摘要 |
Provided is a method for crystallization and purification of a macrolide such as tacrolimus, sirolimus, pimecrolimus, or everolimus that includes the step of providing a combination of a macrolide, and a polar solvent, dopolar aprotic solvent, or hydrocarbon solvent at pH of 7 or above.
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| 申请公布号 |
WO2004089958(B1) |
申请公布日期 |
2005.03.03 |
| 申请号 |
WO2004US10033 |
申请日期 |
2004.03.31 |
| 申请人 |
TEVA GYOGYSZERGYAR RESZVENYTARSASAG;TEVA PHARMACEUTICALS USA, INC.;KERI, VILMOS;CSORVASI, ANDREA |
发明人 |
KERI, VILMOS;CSORVASI, ANDREA |
| 分类号 |
C07D498/22;C12P17/18;(IPC1-7):C07D498/18 |
主分类号 |
C07D498/22 |
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