TIE-2 MODULATORS AND METHODS OF USE,申请号WO2004US08579-传众专利搜索

发明名称	TIE-2 MODULATORS AND METHODS OF USE
摘要	The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Tie-2. Methods of using the compounds and pharmaceutical compositions thereof to treat kinase-dependent diseases and conditions are also an aspect of the invention.
申请公布号	WO2004083235(A3)	申请公布日期	2005.03.03
申请号	WO2004US08579	申请日期	2004.03.19
申请人	EXELIXIS INC.;BANNEN, LYNNE, CANNE;BROWN, S., DAVID;CHENG, WEI;CHEUNG, ATWOOD, KIM;DALRYMPLE, LISA, ESTHER;EPSHTEYN, SERGEY;IBRAHIM, MOHAMED, ABDULKADER;JAMMALAMADAKA, VASU;LEAHY, JAMES, WILLIAM;LEWIS, GARY, LEE;MAC, MORRISON, B.;MANN, LARRY, W.;NUSS, JOHN, M.;NOGUCHI, ROBIN, TAMMIE;PARKS, JASON, JEVIOUS;RIDGWAY, BRIAN, HUGH;SANGALANG, JOAN, C.;SCHNEPP, KEVIN, LUKE;SHI, XIAN;WILLIAMS, MATTHEW, A.;XU, WEI;KHOURY, RICHARD	发明人	BANNEN, LYNNE, CANNE;BROWN, S., DAVID;CHENG, WEI;CHEUNG, ATWOOD, KIM;DALRYMPLE, LISA, ESTHER;EPSHTEYN, SERGEY;IBRAHIM, MOHAMED, ABDULKADER;JAMMALAMADAKA, VASU;LEAHY, JAMES, WILLIAM;LEWIS, GARY, LEE;MAC, MORRISON, B.;MANN, LARRY, W.;NUSS, JOHN, M.;NOGUCHI, ROBIN, TAMMIE;PARKS, JASON, JEVIOUS;RIDGWAY, BRIAN, HUGH;SANGALANG, JOAN, C.;SCHNEPP, KEVIN, LUKE;SHI, XIAN;WILLIAMS, MATTHEW, A.;XU, WEI;KHOURY, RICHARD
分类号	A61K31/496;C07D417/04;C07D417/14;C07K	主分类号	A61K31/496
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