发明名称 |
Method for obtaining vaccines for preventing the pathogenic effects related to a retroviral infection |
摘要 |
The invention provides a method of searching for and obtaining a vaccine against the pathogenic effects related to the infection of an animal or human host by a retrovirus that penetrates into a target cell of the host, and a vaccine obtained by the method are provided. The method includes preparing candidate vaccine agents based on a polypeptide comprising at least part of an envelope protein of a pathogenic strain of the retrovirus and selecting as the vaccine a modified polypeptide chosen from polypeptides that induces an immune response directed against an immunodominant region of an envelope protein of the retrovirus and not against a protein of the host.
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申请公布号 |
US2005048478(A9) |
申请公布日期 |
2005.03.03 |
申请号 |
US20020198938 |
申请日期 |
2002.07.22 |
申请人 |
MYMETICS S.A. |
发明人 |
SERRES PIERRE F. |
分类号 |
C12N15/09;A61K39/00;A61K39/21;A61P31/14;A61P31/18;A61P35/00;A61P37/04;C07K14/155;C07K14/16;C07K16/10;C07K16/22;C07K16/24;C07K16/26;C12N5/02;C12N7/01;C12N15/48;(IPC1-7):C12Q1/68;C12N7/00;C12N7/02;C12N5/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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