发明名称 ISOLATED HEAT-INDUCIBLE CELL SURFACE PROTEIN AND HYPERTHERMIA-BASED TUMOR IMMUNOTARGETING THERAPY
摘要 An isolated, purified and characterized gene comprising a polynucleotide having a sequence shown in Seq. Id. No. 1. An isolated, purified and characterized protein comprising a polypeptide having a sequence shown in Seq. Id. No. 2. In an aspect, a method of activating a gene or inducing the gene encoded protein comprises intentionally applying finite heat for a time and in an amount effective to living cells, tissues, organs or a whole body to cause and thereby causing activation of a gene comprising a polynucleotide having a sequence shown in Seq. Id. No. 1 and production of an encoded protein comprising a polypeptide having a sequence shown in Seq. Id. No. 2. In an aspect, a method of stress including hyperthermia-based tumor immunotargeting therapy for the treatment of neoplasm and pre-cancerous lesions.
申请公布号 WO2005018554(A2) 申请公布日期 2005.03.03
申请号 WO2004US26143 申请日期 2004.08.12
申请人 WASHINGTON UNIVERSITY IN ST. LOUIS 发明人 XU, MAI
分类号 C07K14/705;C07K16/30;G09G3/34;G09G3/36;H04M1/22;H04M1/73 主分类号 C07K14/705
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