摘要 |
An isolated, purified and characterized gene comprising a polynucleotide having a sequence shown in Seq. Id. No. 1. An isolated, purified and characterized protein comprising a polypeptide having a sequence shown in Seq. Id. No. 2. In an aspect, a method of activating a gene or inducing the gene encoded protein comprises intentionally applying finite heat for a time and in an amount effective to living cells, tissues, organs or a whole body to cause and thereby causing activation of a gene comprising a polynucleotide having a sequence shown in Seq. Id. No. 1 and production of an encoded protein comprising a polypeptide having a sequence shown in Seq. Id. No. 2. In an aspect, a method of stress including hyperthermia-based tumor immunotargeting therapy for the treatment of neoplasm and pre-cancerous lesions. |