<p>One aspect of the invention relates to polypeptide multimers that have antiviral and immunogenic activity and compositions and methods for inhibiting viral infectivity. The polypeptide multimers are comprised of at least one monomer with a ratio of N heptads to C heptads of at least about 2:1. Another aspect of the invention relates to antibodies that specifically bind the polypeptide multimers and compositions and methods for inhibiting viral infectivity.</p>
申请公布号
WO2005018666(A1)
申请公布日期
2005.03.03
申请号
WO2003US25295
申请日期
2003.08.14
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, ASREPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES;WEISS, CAROL, D.;HE, YONG;VASSELL, RUSSELL;DE ROSNY, EVE
发明人
WEISS, CAROL, D.;HE, YONG;VASSELL, RUSSELL;DE ROSNY, EVE