| 发明名称 |
Detection and removal of lead using lead-binding proteins |
| 摘要 |
Thymosin beta-4 (TB4), Thymosin beta-9 (TB9), and acyl-CoA binding protein (ACBP) are two proteins that possess the ability to bind lead in human tissue. These two proteins have a high affinity lead-binding region with a dissociation constant (Kd) of about 10<-9 >M that allows for a strong interaction between the metal and the protein. These proteins and their analogs and lead-binding fragments can be used to detect and remove lead from various media.
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| 申请公布号 |
US2005049201(A1) |
申请公布日期 |
2005.03.03 |
| 申请号 |
US20040498292 |
申请日期 |
2004.09.22 |
| 申请人 |
LOWE ADRIAN M.;COLPAS GERARD J.;HAMILTON MAUREEN A.;SALCIUS MICHAEL J.;SANDERS MITCHELL C. |
发明人 |
LOWE ADRIAN M.;COLPAS GERARD J.;HAMILTON MAUREEN A.;SALCIUS MICHAEL J.;SANDERS MITCHELL C. |
| 分类号 |
C07K7/08;C07K14/47;C07K14/575;C12N15/13;G01N33/84;(IPC1-7):A61K38/08;C07K7/06;G01N33/558 |
主分类号 |
C07K7/08 |
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