发明名称 |
Methods for enhancing graft survival by modulating heme oxygenase activity |
摘要 |
Methods are provided wherein the survival of an organ transplant is enhanced by introducing into cells of the transplant a nucleic acid molecule that modulates heme oxygenase-I activity therein. Nucleic acid molecules that modulate heme oxygenase-I activity and therefore find use in the described methods include, for example, molecules that encode a polypeptide that itself exhibits heme oxygenase-I activity or antisense oligonucleotides that act to inhibit heme oxygenase-I activity in a cell.
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申请公布号 |
US6861414(B1) |
申请公布日期 |
2005.03.01 |
申请号 |
US20000515582 |
申请日期 |
2000.02.29 |
申请人 |
SANGSTAT MEDICAL CORPORATION |
发明人 |
BUELOW ROLAND;WOO JACKY;IYER SUHASINI |
分类号 |
C12N15/09;A61K9/127;A61K31/7088;A61K48/00;A61P37/06;A61P43/00;C12N5/02;C12N9/02;C12N15/53;(IPC1-7):A61K31/70;A01N63/00;C12N15/74;C12N15/85 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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