发明名称 ACYLOXYPYRROLIDINE DERIVATIVES AND USE THEREOF AS LIGANDS OF V1B OR BOTH V1B AND V1A RECEPTORS
摘要 The invention relates to acyloxypyrrolidine derivatives of general formula (I): in which: R<SUB>1 </SUB>represents a hydrogen atom, a (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, a (C<SUB>3</SUB>-C<SUB>6</SUB>)cycloalkyl, a group -CH<SUB>2</SUB>CH<SUB>2</SUB>COOH or a group -NR<SUB>2</SUB>R<SUB>3</SUB>; R<SUB>2 </SUB>and R<SUB>3 </SUB>each represent, independently, a hydrogen atom or a (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl. Also disclosed and claimed are the method of preparation of the compounds of the invention and their application in therapeutics.
申请公布号 HRP20041231(A2) 申请公布日期 2005.02.28
申请号 HR2004P001231 申请日期 2004.12.30
申请人 SANOFI-AVENTIS 发明人 ALAIN AULOMBARD;GEORGES GARCIA;ANTOINE PRADINES;CLAUDINE SERRADEIL - LE GAL;JEAN WAGNON
分类号 A61K31/404;A61P1/04;A61P3/04;A61P3/06;A61P3/10;A61P5/00;A61P9/00;A61P9/10;A61P13/12;A61P25/20;A61P25/22;A61P25/24;A61P35/00;C07D403/04 主分类号 A61K31/404
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