| 摘要 |
A PHARMACEUTICAL COMPOSITION COMPRISING: I) AN ANTIFUNGAL AGENT WHICH IS (-)-(2R-CIS)-4-[4-[4-[4-[[-5-(2,4-DIFLUOROPHENYL)-TETRAHYDRO-5-(1 H-1,2,4- TRIAZOL-1-YLMETHYL)FURAN-3-YL]METHOXY]PHENYL]-1-PIPERAZINYL]PHENYL]-2,4-DIHYDRO-2-[(S)-1-ETHYL-2(S)- HYDROXYPROPYL]-3H-1,2,4-TRIAZOL-3-ONE; II) AT LEAST ONE NON-IONIC SURFACTANT; AND III) A DILUENT. THE COMPOSITION ENABLES THE ANTIFUNGAL COMPOUND, WHICH HAS VERY LOW WATER SOLUBILITY, TO HAVE ENHANCED BIOAVAILABILITY IN MAMMALS, SUCH AS HUMANS.
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