发明名称 NOVEL PROCESS FOR PREPARING (+)-CIS-SERTRALINE
摘要 The present invention is directed to (+)-cis-sertraline hydrochloride and methods of preparation. The present invention also includes processes for making sertraline having a cis/trans ratio greater than 3:1, greater than or equal to 8:1, or between about 8:1 and about 12:1, from the Schiff base of sertralone, sertraline-1-imine.
申请公布号 HRP20020773(A2) 申请公布日期 2005.02.28
申请号 HR2002P000773 申请日期 2002.09.25
申请人 TEVA PHARMACEUTICAL INDUSTRIES LTD. 发明人 NEOMI GERSHON;TAMAR NIDAM;MARIOARA MENDELOVICI;GIDEON PILARSKY
分类号 C07B57/00;C07B61/00;C07C209/52;C07C209/88;C07C211/42 主分类号 C07B57/00
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