4-OXO-1, 4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS

摘要

THE PRESENT INVENTION PROVIDES A COMPOUND OF FORMULA I(FORMULA 1) WHEREIN R1 IS C1-7 ALKYL, OPTIONALLY SUBSTITUTED BY HYDROXY OR NR4R5; R2 IS C1-7 ALKYL SUBSTITUTED BY HYDROXY OR NR4R5; R3 IS H, F OR C1-7 ALKOXY; R4 AND R5 TOGETHER WITH N ARE A 5- OR 6-MEMBERED HETEROCYCLIC MOIETY HAVING 1-3 HETEROATOMS SELECTED FROM THE GROUP CONSISTING OF NITROGEN, OXYGEN AND SULFUR IN WHICH SULFUR MAY BE SUBSTITUTED BY ONE (1) OR TWO (2) OXYGEN ATOMS; AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF COMPOUNDS OF FORMULA I OF THE PRESENT INVENTION ARE USEFUL AS ANTIVIRAL AGENTS.