Isopropylidene derivatives of monosaccharides as cell adhesion inhibitors

摘要

Disclosed is the use of compounds of formula I in the manufacture of medicaments for the treatment of disorders associated with cell adhesion molecules, bronchial asthma, rheumatoid arthritis, multiple sclerosis, type I diabetes, psoriasis, allograft rejection and other inflammatory and autoimmune diseases, wherein: R is alkyl, alkene, alkyne, aryl, substituted aryl or alkylaryl, R1 is phenyl, chlorophenyl, tolyl, methoxyphenyl or nitrophenyl, R2 is H, pyrrolidinyl, piperidinyl, morphilinyl, hexamethyleneimino or NHR3. (62) Divided out of 512852