发明名称 METHOD FOR DETECTING FUNCTIONAL ACTIVITY OF CYTOKINS THAT SUPPRESS T-LYMPHOCYTES IN NEONATALS
摘要 FIELD: medicine, immunology. ^ SUBSTANCE: one should carry out reaction of blast-transformation, detect proliferation of T-lymphocytes activated with antibodies to CD3 in the presence of interleukin-7 (ACT IL-7) and in the presence of interleukin-7 and dexametazone (ACT IL-7 D), calculate the index for dexametazone action as the ratio of ACT IL-7 to ACT IL-7 D, moreover, the value of dexametazone action index being above 1.2 indicates increased production of cytokins that suppress T-lymphocytes in neonatals. The method enables to detect functional defect of immune system that characterizes neonatal period. ^ EFFECT: higher efficiency of detection. ^ 2 ex
申请公布号 RU2246732(C2) 申请公布日期 2005.02.20
申请号 RU20030111599 申请日期 2003.04.21
申请人 发明人 TALAEV V.JU.;RUBTSOVA I.E.;LEBEDEVA I.E.
分类号 G01N33/53 主分类号 G01N33/53
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