发明名称 |
Assay for bcr/abl gene rearrangement |
摘要 |
The present invention provides a simple high-throughput assay for detecting bcr/abl translocations. The method includes qualitative PCR methods for identifying the particular amplified translocation (e1a2 or b2a3/b3a2) and real time PCR for quantifying an amount of bcr/abl transcript (e1a2, b2a3 and b3a2). Quantitative measurement of bcr/abl transcript in accordance with the methods of the invention is useful for monitoring response to therapy.
|
申请公布号 |
US2005037373(A1) |
申请公布日期 |
2005.02.17 |
申请号 |
US20030742616 |
申请日期 |
2003.12.18 |
申请人 |
QUEST DIAGNOSTICS INVESTMENTS, INC. |
发明人 |
TSENG RICHARD W.;SAMOSZUK MICHAEL K. |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|