摘要 |
<p>The invention relates to a process for the preparation of an enantiomerically enriched ester, in which a mixture of the enantiomers of the corresponding chiral secondary alcohol in the presence of a racemisation catalyst for the substrate is subjected to an enantioselective acylation with the aid of an acyl donor and a stereoselective acylation catalyst upon which the enantiomerically enriched ester and an acyl donor residue are formed, in the presence of a carbonyl compound and wherein the racemisation catalyst comprises at least one ligand and a metal M chosen from group III<a>, III<b>, IV<b> of the periodic system, preferably Al.</p> |
申请人 |
DSM IP ASSETS B.V.;VERZIJL, GERARDUS, KAREL, MARIA;BROXTERMAN, QUIRINUS, BERNARDUS |
发明人 |
VERZIJL, GERARDUS, KAREL, MARIA;BROXTERMAN, QUIRINUS, BERNARDUS |