The present invention relates to conjugates of hydroxyalkyl starch and a granulocyte colony stimulating factor protein (G-CSF) wherein these conjugat es are formed by a covalent linkage between the hydroxyalkyl starch or a derivative of the hydroxyalkyl starch and the protein. The present invention also relates to the methods of producing these conjugates and the use of the se conjugates.
申请公布号
CA2534418(A1)
申请公布日期
2005.02.17
申请号
CA20042534418
申请日期
2004.08.06
申请人
FRESENIUS KABI DEUTSCHLAND GMBH
发明人
CONRADT, HARALD S.;GRABENHORST, ECKART;SOMMERMEYER, KLAUS;FRANK, RONALD;ZANDER, NORBERT;LUTTERBECK, KATHARINA;EICHNER, WOLFRAM;KNOLLER, HELMUT