<p>There are disclosed novel pyridyl piperazinyl ureas that are potent antagonists of vanilloid receptor, VR1, and are useful for the treatment and/or prevention of i) acute or chronic pain or itch; ii) inflammation; iii) gastrointestinal and urinary tract disorders; and iv) tracheobronchial and diaphragmatic dysfunction in humans.</p>
申请公布号
WO2005014580(A1)
申请公布日期
2005.02.17
申请号
WO2004US25844
申请日期
2004.08.04
申请人
JANSSEN PHARMACEUTICA, N.V.;CARRUTHERS, NICHOLAS, I.;SHAH,, CHANDRAVADAN, R.;SWANSON, DEVIN, M.
发明人
CARRUTHERS, NICHOLAS, I.;SHAH,, CHANDRAVADAN, R.;SWANSON, DEVIN, M.