发明名称 |
PODOPHYLLOTOXIN DERIVATIVES AS IGF-1R INHIBITORS |
摘要 |
The invention refers to new compounds, e.g. podophyllotoxin derivatives, as well as to the use thereof and of known compounds as specific inhibitors of the insulin-like growth factor-1 receptor (IGF-1R). Said compounds can be used for treatment of IGF-1/IGF-1R dependent diseases, such as cancer, psoriasis, arteriosclerosis, certain endocrine and metabolic disorders etc. |
申请公布号 |
WO2004093781(A3) |
申请公布日期 |
2005.02.17 |
申请号 |
WO2004SE00590 |
申请日期 |
2004.04.15 |
申请人 |
BIOVITRUM AB;AXELSON, MAGNUS;LARSSON, OLLE |
发明人 |
AXELSON, MAGNUS;LARSSON, OLLE |
分类号 |
A61K;A61K31/121;A61K31/343;A61K31/353;A61K31/36;A61K31/4355;A61P5/06;A61P9/10;A61P17/06;A61P35/00;C07C49/213;C07D317/48;C07D491/153;C07D493/04;C07D493/14 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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