An oral dosage form comprising a first composition and a second composition, each composition comprising a pharmaceutically acceptable weak base, especially Compound A or a pharmaceutically acceptable salt or solvate thereof, ('the drug') and a pharmaceutically acceptable carrier therefor, wherein the first and second compositions are arranged to release drug at differing release rates on administration such that the rate of release of the drug from the dosage form is substantially independent of pH; a process for preparing such a dosage form and the use of such a dosage form in medicine.
申请公布号
WO2005013935(A2)
申请公布日期
2005.02.17
申请号
WO2004EP08843
申请日期
2004.08.06
申请人
SB PHARMCO PUERTO RICO INC.;HOKE, JOHN, FRANCIS;MARTINI, LUIGI;RE, VINCENZO;SALE, MARK, EDWARD
发明人
HOKE, JOHN, FRANCIS;MARTINI, LUIGI;RE, VINCENZO;SALE, MARK, EDWARD