METHOD FOR IDENTIFYING ACTIVE AND/OR INACTIVE METABOLITES; AND NOVEL ACTIVE METABOLITES

摘要

The present invention relates to a method for determining whether or not a metabolite of a particular lead compound is an active or an inactive compound. Particularly, this method allows an early screening on whether or not a lead compound itself or an active metabolite thereof is a suitable candidate to go through the time- and money consuming route to try and obtain a valuable and marketable pharmaceutical composition. In a second, aspect, the present invention relates to active metabolites found by carrying out the method of the invention.