| 摘要 |
<p>Metathesis catalysts comprising ruthenium complexes with an o-hydrocarbyloxybenzylidene ligand are made by ligand exchange with 2-propenyl-phenoxy compounds which are obtained from allyl phenyl ethers by Claisen rearrangement followed by double bond isomerisation and alkylation of the hydroxyl group or vice versa. A method for the production of metathesis catalysts of formula (5): [Image] R4>H, alkyl or aryl (both optionally substituted); R : alkyl, alkenyl, alkynyl, aryl or heteroaryl (all optionally substituted); a1, b1, c1, d1H, halogen, optionally substituted alkyl, alkenyl, alkynyl, aryl, heteroaryl, alkoxy, alkenyloxy, aryloxy, acyloxy, alkoxycarbonyloxy, carboxyl, alkoxycarbonyl, alkylcarbonyl, alkenylcarbonyl, (hetero)arylcarbonyl, amino, mono- or di-alkyl-amino, mono- or di-acyl-amido, alkyl- or aryl-sulfonylamido, alkyl- or aryl-sulfonylamidocarbonyl, nitro, cyano, alkylthio, alkylsulfinyl or alkylsulfonyl (and corresponding aryl- or heteroaryl- compounds), mono- or di-alkyl-phosphinoyl, mono- or di-aryl-phosphinoyl, alkylarylphosphinoyl, mono- or di-alkoxy-phosphoryl, mono-alkoxy-hydroxy-phosphoryl or dihydroxyphosphoryl; X, X : anionic ligands; L : a neutral ligand The method involves: (a) Claisen rearrangement of a compound of formula (1) to a compound of formula (2); (b) isomerisation of (2) to (3a), or alkylation or arylation on of (2) to (3b); (c) alkylation or arylation of (3a) or isomerisation of (3b) to give a compound (4); and (d) reaction of (4) with a ruthenium complex of formula (6). [Image] R1>-R3>H, alkyl or aryl (both optionally substituted); R9>H, 1-20C alkyl, 2-20C alkenyl, 2-20C alkynyl or aryl; R1>0>aryl, vinyl or allenyl; L5>, L6>neutral ligands Independent claims are also included for (1) E- and Z-[2-(2-propenylphenyloxy)propionic acid methyl ester]; and (2) Compounds of formula (3a), in which a1, b1 and c1H; d : phenyl, 2-alkoxyphenyl, 2-cyclohexyloxyphenyl, isopropoxy or cyclohexyloxy.</p> |
