发明名称 |
Reducing protein a leaching during protein a affinity chromatography |
摘要 |
A method for reducing leaching of protein A during protein A affinity chromatography is described which involves reducing temperature or pH of, or by adding one or more protease inhibitors to, a composition that is subjected to protein A affinity chromatography.
|
申请公布号 |
US2005038231(A1) |
申请公布日期 |
2005.02.17 |
申请号 |
US20040877532 |
申请日期 |
2004.06.24 |
申请人 |
GENENTECH, INC. |
发明人 |
FAHRNER ROBERT L.;LAVERDIERE AMY;MCDONALD PAUL J.;O'LEARY RHONA M. |
分类号 |
C07K16/06;(IPC1-7):C07K16/30;A61K38/00;C07K16/00 |
主分类号 |
C07K16/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|