| 发明名称 |
Enzyme-activated anti-tumor prodrug compounds |
| 摘要 |
Disclosed are enzyme-activated anti-tumor and anti-metastatic prodrug compounds. The specific enzymes are collagenase(IV) and elastase. Also disclosed are methods of making and using such compounds.
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| 申请公布号 |
US6855689(B2) |
申请公布日期 |
2005.02.15 |
| 申请号 |
US20020154507 |
申请日期 |
2002.05.23 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
FIRESTONE RAYMOND A.;TELAN LEILA A. |
| 分类号 |
A61K31/704;A61K38/00;A61K38/07;A61K45/00;A61K47/48;A61P1/00;A61P1/16;A61P11/00;A61P15/00;A61P19/00;A61P25/00;A61P35/00;A61P43/00;C07K5/103;C07K7/06;(IPC1-7):A61K38/00;C07K5/00 |
主分类号 |
A61K31/704 |
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