发明名称 NEUE PYRAZIN-DERIVATE ODER SALZE DAVON, PHARMAZEUTISCHE ZUSAMMENSETZUNGEN, DIE DIE DERIVATE ODER DEREN SALZE ENTHALTEN UND INTERMEDIATE ZU BEIDER HERSTELLUNG
摘要 Pyrazine derivatives represented by general formula Ä1Ü: <CHEM> wherein the variables are as defined in the specification, or salts thereof have an excellent antiviral activity and are useful as a therapeutic agent for treating viral infections. Further, fluoropyrazine-carboxamide derivatives represented by general formula Ä2Ü: <CHEM> wherein the variables are as defined in the specification, or salts thereof are useful as an intermediate for production of the compounds of general formula Ä1Ü, and as an intermediate for production of the fluoropyrazine-carboxamide derivatives of which one typical example is 6-fluoro-3-hyroxy-2-pyrazine-carboxamide having an antiviral activity.
申请公布号 AT288443(T) 申请公布日期 2005.02.15
申请号 AT20010904434T 申请日期 2001.02.14
申请人 TOYAMA CHEMICAL CO., LTD. 发明人 EGAWA, HIROYUKI;FURUTA, YOUSUKE;SUGITA, JUN;UEHARA, SAYURI;HAMAMOTO, SHOICHI;YONEZAWA, KENJI
分类号 A61P31/12;C07H19/04;(IPC1-7):C07H19/04;C07D405/04;C07D241/24;A61K31/706;A61K31/496 主分类号 A61P31/12
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